BACKGROUND:　The　outbreak　of　Ebola　virus　disease　in　West　Africa　has　brought　great　disaster　to　the　people＇s　health　in　affected　countries.　China　dispatched　first　group　of　public　health　experts　and　medical　staff　to　Sierra　Leone　in　September　2014　to　fight　Ebola.　METHODS:　To　systematically　collect　huge　amount　of　primary　data,　and　to　make　analysis,　draw　conclusions　and　lessons　in　terms　of　six　aspects,　respectively　as　training　before　departure,　local　disease　information,　track　of　epidemic　situation,　transformation　of　temporary　laboratory,　detection　of　Ebola　virus　samples　as　well　as　assessment　through　single　blind　test.　RESULTS:　1)　Our　team　has　launched　preparatory　works　in　advance　before　going　to　Sierra　Leone.　2)　Malaria　is　the　country＇s　severest　infectious　disease.　3)　Observation　centers　were　overcrowded　with　large　number　of　suspected　cases　being　inspected,　implying　high　risk　of　nosocomial　infection.　4)　A　BSL-II　laboratory　with　3　work　areas　and　2　buffer　areas　was　built,　achieving　several　major　functions　within　6　days.　5)　Confirmed　by　South　African　Raqqa　laboratory,　our　detection　accuracy　reached　100%.　6)　At　one　week　before　return,　the　daily　average　sample　amount　of　our　team　reached　66　cases　and　our　detection　capability　was　equivalent　to　that　of　USA.　CONCLUSIONS:　Successful　experience　from　fighting　against　Ebola　in　Sierra　Leone　could　be　summarized　as:　1)　Optimized　processes　and　scientific　security　measures　are　prerequisite　to　improving　the　detection　ability.　2)　The　close　collaboration　between　laboratory　and　observation　center　has　created　a　new　model　of　China＇s　foreign　aid.　3)　Comprehensive　information　investigation　and　training　lay　a　solid　foundation　for　the　successful　completion　of　tasks　(Tab.　1,　Ref.　3).　Text　in　PDF　www.elis.sk.