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Abstract:
In the presence of Pd-2(dba)(3)center dot CHCl3(2.5 mol%), PPh3(10 mol%), and 60% NaH (1.5 equiv), the formal [5+3] cycloaddition between isatin-based alpha-(trifluoromethyl)imines and vinyloxiranes proceeded readily in 1,2-DCE at 40 celcius and affordedcis-configured medium-heterocycle-fused spirooxindoles in the reasonable chemical yields with >20:1 dr. The relative stereochemical configuration of the title products was identified by X-ray diffraction analysis.
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SYNLETT
ISSN: 0936-5214
Year: 2020
Issue: 01
Volume: 32
Page: 57-62
2 . 0 0 0
JCR@2022
ESI Discipline: CHEMISTRY;
ESI HC Threshold:139
Cited Count:
WoS CC Cited Count: 9
SCOPUS Cited Count: 8
ESI Highly Cited Papers on the List: 0 Unfold All
WanFang Cited Count:
Chinese Cited Count:
30 Days PV: 0
Affiliated Colleges: