• Complex
  • Title
  • Keyword
  • Abstract
  • Scholars
  • Journal
  • ISSN
  • Conference
搜索

Author:

Liu Ya-qi (Liu Ya-qi.) | Gao Mei-juan (Gao Mei-juan.) | Xu Yi-zhuang (Xu Yi-zhuang.) | Sun Qi-gang (Sun Qi-gang.) | Zhang Xiao-qing (Zhang Xiao-qing.) | Xu Zhi (Xu Zhi.) | Zhang Yuan-fu (Zhang Yuan-fu.) | Wu Jin-guang (Wu Jin-guang.) | Zhou Xiaa-si (Zhou Xiaa-si.) | Ling Xiao-feng (Ling Xiao-feng.)

Indexed by:

EI Scopus SCIE PKU CSCD

Abstract:

The aim of the study is to explore the possibility of detecting metastatic lymph nodes by FTIR spectra during the surgery of thyroid cancer. The FTIR spectra of 20 metastatic lymph nodes and 69 non-metastatic ones were collected via an ATR (attenuated total reflectance) probe. For each spectrum, 28 variables of 13 bands including peak positions and relative intensities were measured. The variables of metastatic lymph node were compared to those of non-metastatic ones using standard statistic methods. The results indicated that the FTIR spectra of metastatic lymph nodes were significantly different from non-metastatic ones in the bands related to protein, lipid, nucleic acid and carbohydrate. ( 1) Variations of bands related to protein: The relative intensity ratios Of I-3 280/I-1 460, I-1 640/I-1 460 and I-1 546/I-1 460 increased significantly (P<0.05); (2) Variations of bands related to lipid: The relative intensity ratios of I-1 743/I-1 460 decreased significantly (P<0.05). On the contrary, I-1 400/I-1 460 increased significantly (P<0.05); (3) The peak positions of 1 165 and 1 120 cm(-1) which were all assigned to carbohydrate shifted toward higher wave number (P<0.05). The relative intensity ratio of I-1 165/I-1 460 decreased significantly (P<0.05); (4) The peak positions of 1 085 cm(-1) related to nucleic acid shifted to the lower wave number (P<0.05); (5) Other undetermined bands: The relative intensity ratios of I-1 303/I-1 460 and I-1 303/I-1 240 increased significantly (P<0.05). FTIR spectroscopy could be a reliable and practicable method for metastatic lymph nodes diagnosis in the operation of thyroid cancer. It could be applied in detecting metastatic lymph nodes which can not be determined by palpation in surgery.

Keyword:

Thyroid cancer FTIR Lymph node

Author Community:

  • [ 1 ] [Liu Ya-qi]Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100191, Peoples R China
  • [ 2 ] [Gao Mei-juan]Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100191, Peoples R China
  • [ 3 ] [Sun Qi-gang]Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100191, Peoples R China
  • [ 4 ] [Zhang Xiao-qing]Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100191, Peoples R China
  • [ 5 ] [Xu Zhi]Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100191, Peoples R China
  • [ 6 ] [Zhou Xiaa-si]Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100191, Peoples R China
  • [ 7 ] [Ling Xiao-feng]Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100191, Peoples R China
  • [ 8 ] [Xu Yi-zhuang]Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China
  • [ 9 ] [Zhang Yuan-fu]Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China
  • [ 10 ] [Wu Jin-guang]Peking Univ, Coll Chem & Mol Engn, Beijing 100871, Peoples R China
  • [ 11 ] [Gao Mei-juan]Beijing Univ Technol, Sch Hosp, Beijing 100124, Peoples R China

Reprint Author's Address:

  • [Ling Xiao-feng]Peking Univ, Dept Gen Surg, Hosp 3, Beijing 100191, Peoples R China

Show more details

Related Keywords:

Source :

SPECTROSCOPY AND SPECTRAL ANALYSIS

ISSN: 1000-0593

Year: 2009

Issue: 11

Volume: 29

Page: 2917-2921

0 . 7 0 0

JCR@2022

ESI Discipline: CHEMISTRY;

Cited Count:

WoS CC Cited Count: 4

SCOPUS Cited Count:

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

Affiliated Colleges:

Online/Total:1297/5382037
Address:BJUT Library(100 Pingleyuan,Chaoyang District,Beijing 100124, China Post Code:100124) Contact Us:010-67392185
Copyright:BJUT Library Technical Support:Beijing Aegean Software Co., Ltd.