Urban　networks　are　typical　multiplex　networks　with　different　forms　of　spatial　interactions　between　cities,　including　spatial　interactions　among　humans,　material　and　information.　It　is　important　to　systemically　explore　multiplex　urban　networks　to　understand　the　operation　of　complex　urban　systems　and　formulate　policies　for　urban　planning　and　regional　development.　However,　studies　investigating　interurban　networks　from　the　multiplexity-based　perspective　are　still　in　their　infancy.　Therefore,　this　study　collects　records　from　social　media　to　construct　a　multiplex　urban　network　with　two　layers　that　represent　information　flows　and　population　mobility.　The　results　of　the　topological　properties　analysis　confirm　that　a　high　correlation　exists　between　information　resources　and　human　capital,　and　there　is　a　strong　driving　force　from　human　capital　to　information　flows.　In　addition,　the　joint　effects　of　these　two　types　of　resources　on　urban　development　are　analyzed,　and　the　cross-layer　resource　clustering　ability　of　cities　is　discussed.　Several　implications　for　urban　economic　development　planning　and　orientation　that　could　support　macroscopic　policy-making　are　provided.