This　paper　summarized　the　recent　6　years＇　progress　of　anti-HIV　compounds　and　traditional　Chinese　medicines　by　searching　international　network　and　reviewing　the　domestic　and　foreign　literature.　Traditional　Chinese　medicinal　appeared　to　be　a　rich　source　of　potentially　useful　materials　for　the　treatment　of　human　immunodeficiency　virus　infection.　Some　of　them　are　much　more　potent　in　anti-HIV　activity.　And　some　components　extracted　from　the　herbs　are　even　more　tonic　than　the　crude　herb　medicines.　It　has　been　proved　that　some　active　components　such　as　alkaloids,　proteins,　flavonoids,　quercetin,　terpene,　lignanoid　are　able　to　work　on　anti-HIV.　People　should　pay　more　attention　to　the　study　of　traditional　Chinese　medicine　and　the　leading　compounds　on　anti-HIV/AIDS　in　the　clinic　and　in　the　laboratory.　So　searching　for　high　efficacy　and　low　toxicity　anti-HIV　drug　from　traditional　Chinese　medicine　is　an　important　and　prospective　research　direction　in　the　future.