Based　on　the　blasting　engineering　of　the　subway　tunnel,　the　overall　dynamic　response　of　the　28-story　frame-shear-wall　structure　is　studied　by　field　test　and　numerical　analysis.　Field　test　is　the　blasting　vibration　monitoring　and　operational　mode　analysis　(OMA).　OMA　used　Ibrahim　Time　Domain　method　to　extract　the　modal　frequencies,　the　modal　damping　ratio　of　the　structure,　provided　the　basis　for　further　analysis　of　the　vibration　response　laws.　The　structure　is　simplified　into　a　mass-spring-damper　model.　Based　on　the　modal　parameters　extracted　from　the　AVT,　fixed　the　stiffness　matrix　and　the　damping　matrix　of　the　mass-spring-damper　model,　and　set　up　the　dynamic　differential　equation.　So　the　modal　parameters　and　frequency-response-functions　of　the　building　bending　vibration　can　be　calculated.　SIMULINK　dynamic　simulation　model　was　established　based　on　the　dynamic　differential　equation　of　the　mass-spring-damper　model.　Based　on　the　blasting　vibration　velocity　signal,　the　overall　vibration　response　law　of　high-rise　buildings　under　tunnel　blasting　seismic　is　analyzed.　The　following　conclusions　are　drawn:　1.　Under　the　blasting　vibration　of　the　subway　tunnel,　the　vibration　response　velocity　of　high-rise　buildings　presents:　vertical　vibration　is　the　largest,　lengthways　vibration　velocity　is　the　second,　and　transverse　vibration　velocity　is　the　smallest.　However,　the　vertical　vibration　velocity　peak　and　tangential　vibration　velocity　peak　at　the　higher　floors　is　not　much　different.　2.　On　the　higher　floors,　the　velocity　peaks　fluctuated　with　floor　increasing,　and　fluctuation　is　interrelated　with　the　dominant　mode.　The　peak　value　of　vibration　velocities　distribution　shows　this　correlation;　3,　To　simplify　the　high-rise　building　to　be　the　mass-spring-damper　model　and　set　up　the　mathematical　model　of　dynamic　reaction.　Then,　the　Simulink　simulation　model　was　established　for　simulation　calculation.　This　method　can　adequately　predict　the　response　of　the　structure　under　blasting　vibration.