Since　the　onset　of　the　21st　century,　the　number　of　data　centers　has　been　increasing　continuously,　and　the　energy　consumption　of　these　data　centers　has　aroused　people＇s　attention.　Many　experiments　have　been　conducted　to　reduce　the　energy　consumption　in　data　center　cooling,　and　free　cooling　utilization　based　on　the　mechanically　driven　two-phase　cooling　loop　(MTCL)　system　has　been　proven　to　be　an　effective　solution　for　energy　saving.　This　paper　reviews　the　research　on　and　developments　in　the　practical　application　of　the　MTCL　system　for　data　center　cooling　in　recent　decades.　It　presents　a　detailed　summary　of　the　progress　of　research　on　the　MTCL　system　in　data　centers.　The　aim　is　to　provide　an　improved　understanding　of　the　system　and　promote　the　application　of　this　system　in　data　center　energy　saving.