A　six-degree-of-freedom　(6DOF)　control　scheme　is　proposed　for　the　glide　phase　of　hypersonic　vehicle.　Based　on　hypersonic　vehicle　motion　and　engagement　model,　the　3D　integrated　guidance　and　control　(IGC)　model　is　constructed.　The　backstepping-high　order　sliding　mode　(BHOSM)　control　scheme　is　proposed　based　on　backstepping　method　and　the　high-order　sliding　mode　(HOSM)　method.　The　backstepping　controller　is　designed　to　solve　the　problem　of　under-actuation　in　the　IGC　model.　The　HOSM　controller　is　designed　to　overcome　the　uncertainty,　strong　coupling　and　nonlinear　problems　of　IGC　system.　According　to　Lyapunov＇s　theorem,　the　states　of　the　closed　loop　system　are　proved　to　be　uniform　bounded.　Finally,　the　effectiveness　and　reliability　of　the　proposed　method　is　verified　and　studied　by　simulation　experiments.　©　2023　Technical　Committee　on　Control　Theory,　Chinese　Association　of　Automation.