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Author:

Yang, Bin (Yang, Bin.) | Li, Jianqiang (Li, Jianqiang.) | Wang, Jingyi (Wang, Jingyi.) | Li, Ruiqi (Li, Ruiqi.) | Gu, Ke (Gu, Ke.) | Liu, Bo (Liu, Bo.)

Indexed by:

EI Scopus SCIE

Abstract:

Rapid and accurate identification of cancerous areas during surgery is crucial for guiding surgical procedures and reducing postoperative recurrence rates. Dynamic Cell Imaging (DCI) has emerged as a promising alternative to traditional frozen section pathology, offering high-resolution displays of tissue structures and cellular characteristics. However, challenges persist in segmenting DCI images using deep learning methods, such as color variation and artifacts between patches in whole slide DCI images, and the difficulty in obtaining precise annotated data. In this paper, we introduce a novel two-stage framework for DCI image generation and segmentation. Initially, the Dual Semantic Diffusion Model (DSDM) is specifically designed to generate high-quality and semantically relevant DCI images. These images not only serve as an effective means of data augmentation to assist downstream segmentation tasks but also help in reducing the reliance on expensive and hard-to-obtain large annotated medical image datasets. Furthermore, we reuse the pretrained DSDM to extract diffusion features, which are then infused into the segmentation network via a cross-attention alignment module. This approach enables our network to capture and utilize the characteristics of DCI images more effectively, thereby significantly enhancing segmentation results. Our method was validated on the DCI dataset and compared with other methods for image generation and segmentation. Experimental results demonstrate that our method achieves superior performance in both tasks, proving the effectiveness of the proposed model.

Keyword:

Semantics Biomedical imaging Oncological surgery Cancer detection Image color analysis Image segmentation image segmentation Image synthesis Semantic diffusion model Noise reduction Medical diagnostic imaging image synthesis Surgery dynamic cell imaging Task analysis

Author Community:

  • [ 1 ] [Yang, Bin]Beijing Univ Technol, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 2 ] [Li, Jianqiang]Beijing Univ Technol, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 3 ] [Wang, Jingyi]Beijing Univ Technol, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 4 ] [Li, Ruiqi]Beijing Univ Technol, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 5 ] [Gu, Ke]Beijing Univ Technol, Fac Informat Technol, Beijing 100124, Peoples R China
  • [ 6 ] [Liu, Bo]Massey Univ, Sch Math & Computat Sci, Auckland 0632, New Zealand

Reprint Author's Address:

  • [Liu, Bo]Massey Univ, Sch Math & Computat Sci, Auckland 0632, New Zealand;;

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Source :

IEEE ACCESS

ISSN: 2169-3536

Year: 2024

Volume: 12

Page: 37702-37714

3 . 9 0 0

JCR@2022

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count: 3

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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