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Author:

Huang, Li (Huang, Li.) | Shea, Andrew L. (Shea, Andrew L..) | Qian, Huining (Qian, Huining.) | Masurkar, Aditya (Masurkar, Aditya.) | Deng, Hao (Deng, Hao.) | Liu, Dianbo (Liu, Dianbo.)

Indexed by:

SSCI EI Scopus SCIE PubMed

Abstract:

Electronic medical records (EMRs) support the development of machine learning algorithms for predicting disease incidence, patient response to treatment, and other healthcare events. But so far most algorithms have been centralized, taking little account of the decentralized, non-identically independently distributed (non-IID), and privacy-sensitive characteristics of EMRs that can complicate data collection, sharing and learning. To address this challenge, we introduced a community-based federated machine learning (CBFL) algorithm and evaluated it on non-IID ICU EMRs. Our algorithm clustered the distributed data into clinically meaningful communities that captured similar diagnoses and geographical locations, and learnt one model for each community. Throughout the learning process, the data was kept local at hospitals, while locally-computed results were aggregated on a server. Evaluation results show that CBFL outperformed the baseline federated machine learning (FL) algorithm in terms of Area Under the Receiver Operating Characteristic Curve (ROC AUC), Area Under the Precision-Recall Curve (PR AUC), and communication cost between hospitals and the server. Furthermore, communities' performance difference could be explained by how dissimilar one community was to others.

Keyword:

Autoencoder Non-IID Critical care Distributed clustering Federated machine learning

Author Community:

  • [ 1 ] [Huang, Li]Tsinghua Univ, Acad Arts & Design, Beijing 10084, Peoples R China
  • [ 2 ] [Huang, Li]Tsinghua Univ, Future Lab, Beijing 10084, Peoples R China
  • [ 3 ] [Shea, Andrew L.]MIT, Comp Sci & Artificial Intelligence Lab, 77 Massachusetts Ave, Cambridge, MA 02139 USA
  • [ 4 ] [Liu, Dianbo]MIT, Comp Sci & Artificial Intelligence Lab, 77 Massachusetts Ave, Cambridge, MA 02139 USA
  • [ 5 ] [Qian, Huining]Beijing Univ Technol, Coll Appl Math & Phys Sci, Beijing 100124, Peoples R China
  • [ 6 ] [Masurkar, Aditya]Northeastern Univ, Sch Engn, Boston, MA 02115 USA
  • [ 7 ] [Deng, Hao]Massachusetts Gen Hosp, Dept Anesthesia Crit Care & Pain Med, Boston, MA 02115 USA
  • [ 8 ] [Deng, Hao]Johns Hopkins Univ, Sch Publ Hlth, Baltimore, MD USA
  • [ 9 ] [Deng, Hao]Boston Childrens Hosp, Boston, MA 02115 USA
  • [ 10 ] [Liu, Dianbo]Boston Childrens Hosp, Boston, MA 02115 USA
  • [ 11 ] [Liu, Dianbo]Harvard Univ, Med Sch, Boston, MA 02115 USA

Reprint Author's Address:

  • [Liu, Dianbo]MIT, Comp Sci & Artificial Intelligence Lab, 77 Massachusetts Ave, Cambridge, MA 02139 USA

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Source :

JOURNAL OF BIOMEDICAL INFORMATICS

ISSN: 1532-0464

Year: 2019

Volume: 99

4 . 5 0 0

JCR@2022

ESI Discipline: COMPUTER SCIENCE;

ESI HC Threshold:147

JCR Journal Grade:2

Cited Count:

WoS CC Cited Count: 238

SCOPUS Cited Count: 322

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 1

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