Indexed by：
Abstract：
In order to discover activated ingredient form Chinese herbal medicine and to bind KA-01and its main ingredients to HBsAg and HBeAg protein in CM5 by BIAcore 3000, the HepG2.2.15 cell was cultured in vitro to observe the inhibitory effect of KA-01 and its main ingredient. The inhibitory effect of KA-01 and its main ingredients on protein secretion of HBV were tested by Laser Confocal Microscope. The results indicated that the value of KA-01and its main ingredients of A, B, C, D binding with HBsAg protein were 200, 183.7, 162.1, 39.1, 66.6 RU respectively, but almost 0 with HBeAg protein. The inhibitory effect of KA-01 on secretion of HBsAg and HBeAg were 62.01% and 30.59% respectively. The inhibitory effect of A on secretion of HBsAg and HBeAg were 54.26% and 14.15% respectively. The inhibitory effect of B on secretion of HBsAg and HBeAg were 50.97% and 27.92% respectively. The inhibitory effect of C on secretion of HBsAg and HBeAg were 17.54% and 8.06% respectively. The conclusion is that KA-01and its main ingredients of A, B have the inhibitory effect on HBV.
Keyword：
Reprint Author's Address：
Email：
Source ：
Journal of Beijing University of Technology
ISSN： 0254-0037
Year： 2009
Issue： 9
Volume： 35
Page： 1291-1296
Cited Count：
WoS CC Cited Count： 0
SCOPUS Cited Count：
ESI Highly Cited Papers on the List： 0 Unfold All
WanFang Cited Count：
Chinese Cited Count：
30 Days PV： 1
Affiliated Colleges：
