We　propose　to　generate　a　realistic　soft　SUSY　breaking　spectrum　for　Next-to-Minimal　Supersymmetric　Standard　Model　(NMSSM)　with　a　generalized　deflected　mirage　mediation　scenario,　in　which　additional　Yukawa　and　gauge　mediation　contributions　are　included　to　deflect　the　renormalization　group　equation　trajectory.　Based　on　the　Wilsonian　effective　action　obtained　by　integrating　out　the　messengers,　the　NMSSM　soft　SUSY　breaking　spectrum　can　be　given　analytically　at　the　messenger　scale.　We　find　that　additional　contributions　to　mS2　can　possibly　ameliorate　the　stringent　constraints　from　the　electroweak　symmetry　breaking　and　125　GeV　Higgs　mass.　Constraints　from　dark　matter　and　fine-tuning　are　also　discussed.　The　Barbieri-Giudice　fine-tuning　measure　and　electroweak　fine-tuning　measure　in　our　scenario　can　be　as　low　as　O(1),　which　possibly　indicates　that　our　scenario　is　natural.