• Complex
  • Title
  • Keyword
  • Abstract
  • Scholars
  • Journal
  • ISSN
  • Conference
搜索

Author:

Li, Wan (Li, Wan.) | Yang, Chunlan (Yang, Chunlan.) | Shi, Feng (Shi, Feng.) | Wang, Qun (Wang, Qun.) (Scholars:王群) | Wu, Shuicai (Wu, Shuicai.) (Scholars:吴水才) | Lu, Wangsheng (Lu, Wangsheng.) | Li, Shaowu (Li, Shaowu.) | Nie, Yingnan (Nie, Yingnan.) | Zhang, Xin (Zhang, Xin.)

Indexed by:

SSCI Scopus SCIE PubMed

Abstract:

Normal aging has been linked with the decline of cognitive functions, such as memory and executive skills. One of the prominent approaches to investigate the age-related alterations in the brain is by examining the cortical brain connectome. IBASPM is a toolkit to realize individual atlas-based volume measurement. Hence, this study seeks to determine what further alterations can be revealed by cortical brain networks formed by IBASPM-extracted regional gray matter volumes. We found the reduced strength of connections between the superior temporal pole and middle temporal pole in the right hemisphere, global hubs as the left fusiform gyrus and right Rolandic operculum in the young and aging groups, respectively, and significantly reduced inter-module connection of one module in the aging group. These new findings are consistent with the phenomenon of normal aging mentioned in previous studies and suggest that brain network built with the IBASPM could provide supplementary information to some extent. The individualization of morphometric features extraction deserved to be given more attention in future cortical brain network research.

Keyword:

Graph theory IBASPM Cortical brain network Normal aging Regional gray matter volume

Author Community:

  • [ 1 ] [Li, Wan]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 2 ] [Yang, Chunlan]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 3 ] [Wu, Shuicai]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 4 ] [Nie, Yingnan]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 5 ] [Zhang, Xin]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 6 ] [Shi, Feng]Cedars Sinai Med Ctr, Biomed Imaging Res Inst, Dept Biomed Sci, Los Angeles, CA 90048 USA
  • [ 7 ] [Wang, Qun]Tiantan Hosp, Dept Internal Neurol, Beijing, Peoples R China
  • [ 8 ] [Lu, Wangsheng]Puhua Int Hosp, Dept Internal Neurol, Beijing, Peoples R China
  • [ 9 ] [Li, Shaowu]Neurosurg Inst, Dept Funct Neuroimaging, Beijing, Peoples R China

Reprint Author's Address:

  • [Yang, Chunlan]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China

Show more details

Related Keywords:

Related Article:

Source :

BRAIN TOPOGRAPHY

ISSN: 0896-0267

Year: 2018

Issue: 4

Volume: 31

Page: 577-590

2 . 7 0 0

JCR@2022

ESI Discipline: NEUROSCIENCE & BEHAVIOR;

ESI HC Threshold:189

Cited Count:

WoS CC Cited Count: 4

SCOPUS Cited Count: 4

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 1

Online/Total:879/5363133
Address:BJUT Library(100 Pingleyuan,Chaoyang District,Beijing 100124, China Post Code:100124) Contact Us:010-67392185
Copyright:BJUT Library Technical Support:Beijing Aegean Software Co., Ltd.