The　dynamics　of　bacterial　communities　in　a　full-scale　wastewater　treatment　plant　(WWTP)　were　investigated　using　Illumina　MiSeq　sequencing　and　PICRUSt　(phylogenetic　investigation　of　communities　by　reconstruction　of　unobserved　states)　over　a　one-year　period.　Results　showed　that　the　temporal　dynamics　of　structure,　diversity　and　abundance　of　bacterial　community　were　not　obvious.　The　persistent　species　had　low　diversity　but　high　relative　abundance.　Dechloromonas,　Thauera,　Nitrosomonas　and　Nitrospira　were　the　four　dominant　persistent　genera.　The　intermittent　and　transient　genera　showed　different　dynamics　with　persistent　genera.　Variation　partitioning　analysis　suggested　that　water　quality　indexes　(13.40%)　had　the　greatest　contribution　to　bacterial　community　variation,　followed　by　temperature　(9.20%).　Quantitative　polymerase　chain　reaction　analysis　revealed　the　stable　abundances　of　nitrifying　and　denitrifying　bacteria,　and　the　occurrence　of　complete　ammonia　oxidizers　(Comammox)　in　the　full-scale　WWTP.　Functional　prediction　showed　that　the　bacterial　functional　compositions　were　also　relatively　stable,　and　metabolism　was　the　most　dominant　functional　category.　Many　genes　involved　in　the　nitrogen　metabolism　pathway　were　predicted　to　be　present　with　high　gene　counts,　e.　g.,　nirB,　nirD,　nasA,　norB,　nirK,　nosZ　and　nifH.　Most　of　these　genes　were　predicted　to　be　mainly　contributed　by　Rhizobiales,　Burkholderiales,　Rhodocyclales　and　Actinomycetales.　Overall,　the　composition　and　function　of　bacterial　community　in　a　long-term　monitoring　were　relatively　stable,　which　is　important　for　maintaining　the　high　wastewater　treatment　capability　in　full-scale　WWTPs.