Research Progresses on Scoring Function Design and RNA-binding Site Identification in Protein-RNA Docking - 文章详情页

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Molecular　docking　is　one　of　the　effective　methods　for　studying　the　interaction　and　recognition　between　protein　and　RNA.　The　reasonable　design　of　scoring　functions　and　accurate　RNA-binding　site　identification　are　critical　to　the　successful　prediction　of　protein-RNA　complex　structures.　In　this　paper,　the　research　progresses　on　the　two　important　aspects　involved　in　protein-RNA　docking　study　including　scoring　function　design　and　RNA-binding　site　prediction　were　reviewed.　And　a　comparison　for　these　currently　proposed　methods　was　made.　Finally,　the　major　difficulties　were　analyzed　in　the　two　aspects　and　the　development　direction　in　the　future　was　discussed.　©　2017,　Editorial　Department　of　Journal　of　Beijing　University　of　Technology.　All　right　reserved.

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Molecular docking; Protein-RNA interactions; RNA-binding site prediction; Scoring function

作者机构：

[ 1 ] [Li, C.]College of Life Science and Bioengineering, Beijing University of Technology, Beijing, 100124, China
[ 2 ] [Liu, Y.]College of Life Science and Bioengineering, Beijing University of Technology, Beijing, 100124, China
[ 3 ] [Lu, L.]College of Life Science and Bioengineering, Beijing University of Technology, Beijing, 100124, China
[ 4 ] [Ma, M.]College of Life Science and Bioengineering, Beijing University of Technology, Beijing, 100124, China
[ 5 ] [Tan, J.]College of Life Science and Bioengineering, Beijing University of Technology, Beijing, 100124, China
[ 6 ] [Zhang, X.]College of Life Science and Bioengineering, Beijing University of Technology, Beijing, 100124, China
[ 7 ] [Wang, C.]College of Life Science and Bioengineering, Beijing University of Technology, Beijing, 100124, China

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