Conventional　structural　design　methods　mainly　concern　the　demands　of　individual　hazards,　while　a　multi-hazard　oriented　design　method　is　in　great　need　in　the　ever-complex　multi-hazard　building　environment.　Earthquake　and　progressive　collapse,　which　are　the　two　most　critical　encountered　threats　of　reinforced　concrete　(RC)　frames,　are　considered　in　this　study.　Previous　study　indicates　that　the　newly　added　reinforcement　in　progressive　collapse　design　may　weaken　the　structural　seismic　resistance　due　to　＂strong-beam-weak-column＂　failure　mode.　To　resolve　such　confliction,　a　novel　structural　detailing　is　proposed.　Both　cyclic　and　progressive　collapse　tests　are　conducted　to　validate　the　performance　of　the　newly　proposed　reinforcement　arrangement.　The　experimental　results　showed　that　the　proposed　RC　frame　structural　detailing　can　maintain　satisfying　progressive　collapse　resistance　and　efficiently　mitigate　the　column　and　joint　damage　under　cyclic　load.　©　2018　Ingenta.