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作者:

Cheng, Cheng (Cheng, Cheng.) | Wang, Shutong (Wang, Shutong.) | Wu, Jayne (Wu, Jayne.) | Yu, Yongchao (Yu, Yongchao.) | Li, Ruozhou (Li, Ruozhou.) | Eda, Shigetoshi (Eda, Shigetoshi.) | Chen, Jiangang (Chen, Jiangang.) | Feng, Guoying (Feng, Guoying.) | Lawrie, Benjamin (Lawrie, Benjamin.) | Hu, Anming (Hu, Anming.)

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Scopus SCIE PubMed

摘要:

This work presents an aptamer-based, highly sensitive and specific sensor for atto- to femtomolar level detection of bisphenol A (BPA). Because of its widespread use in numerous products, BPA enters surface water from effluent discharges during its manufacture, use, and from waste landfill sites throughout the world. On-site measurement of BPA concentrations in water is important for evaluating compliance with water quality standards or environmental risk levels of the harmful compound in the environment. The sensor in this work is porous, conducting, interdigitated electrodes that are formed by laser-induced carbonization of flexible polyimide sheets. BPA-specific aptamer is immobilized on the electrodes as the probe, and its binding with BPA at the electrode surface is detected by capacitive sensing. The binding process is aided by ac electroosmotic effect that accelerates the transport of BPA molecules to the nanoporous graphene-like structured electrodes. The sensor achieved a limit of detection of 58.28 aM with a response time of 20 s. The sensor is further applied for recovery analysis of BPA spiked in surface water. This work provides an affordable platform for highly sensitive, real time, and field-deployable BPA surveillance critical to the evaluation of the ecological impact of BPA exposure.

关键词:

aptasensor capacitive sensing ac electroosmosis laser direct writing point of care

作者机构:

  • [ 1 ] [Cheng, Cheng]Univ Tennessee, Dept Elect Engn & Comp Sci, 1520 Middle Dr, Knoxville, TN 37996 USA
  • [ 2 ] [Wu, Jayne]Univ Tennessee, Dept Elect Engn & Comp Sci, 1520 Middle Dr, Knoxville, TN 37996 USA
  • [ 3 ] [Wang, Shutong]Univ Tennessee, Dept Mech Aerosp & Biomed Engn, 1512 Middle Dr, Knoxville, TN 37996 USA
  • [ 4 ] [Yu, Yongchao]Univ Tennessee, Dept Mech Aerosp & Biomed Engn, 1512 Middle Dr, Knoxville, TN 37996 USA
  • [ 5 ] [Li, Ruozhou]Univ Tennessee, Dept Mech Aerosp & Biomed Engn, 1512 Middle Dr, Knoxville, TN 37996 USA
  • [ 6 ] [Hu, Anming]Univ Tennessee, Dept Mech Aerosp & Biomed Engn, 1512 Middle Dr, Knoxville, TN 37996 USA
  • [ 7 ] [Eda, Shigetoshi]Univ Tennessee, Inst Agr, Dept Forestry Wildlife & Fisheries, 2431 Joe Johnson Dr, Knoxville, TN 37996 USA
  • [ 8 ] [Chen, Jiangang]Univ Tennessee, Dept Publ Hlth, 1914 Andy Holt Ave, Knoxville, TN 37996 USA
  • [ 9 ] [Wang, Shutong]Sichuan Univ, Coll Elect & Informat Engn, 24 South Sect 1,Yihuan Rd, Chengdu 610065, Peoples R China
  • [ 10 ] [Feng, Guoying]Sichuan Univ, Coll Elect & Informat Engn, 24 South Sect 1,Yihuan Rd, Chengdu 610065, Peoples R China
  • [ 11 ] [Lawrie, Benjamin]Oak Ridge Natl Lab, Comp Sci & Engn Div, Oak Ridge, TN 37831 USA
  • [ 12 ] [Hu, Anming]Beijing Univ Technol, Inst Laser Engn, 100 Pingleyuan, Beijing 100124, Peoples R China

通讯作者信息:

  • [Wu, Jayne]Univ Tennessee, Dept Elect Engn & Comp Sci, 1520 Middle Dr, Knoxville, TN 37996 USA;;[Hu, Anming]Univ Tennessee, Dept Mech Aerosp & Biomed Engn, 1512 Middle Dr, Knoxville, TN 37996 USA;;[Hu, Anming]Beijing Univ Technol, Inst Laser Engn, 100 Pingleyuan, Beijing 100124, Peoples R China

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来源 :

ACS APPLIED MATERIALS & INTERFACES

ISSN: 1944-8244

年份: 2016

期: 28

卷: 8

页码: 17784-17792

9 . 5 0 0

JCR@2022

ESI学科: MATERIALS SCIENCE;

ESI高被引阀值:305

中科院分区:2

被引次数:

WoS核心集被引频次: 102

SCOPUS被引频次: 118

ESI高被引论文在榜: 0 展开所有

万方被引频次:

中文被引频次:

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