Background:　BJUT-II　VAD　is　a　novel　left　ventricular　assist　device　(LVADs),　directly　implanted　into　the　ascending　aorta.　The　pulsatile　support　mode　is　proposed　to　achieve　better　unloading　performance　than　constant　speed　mode.　However,　the　hemodynamic　effects　of　this　support　mode　on　the　aorta　are　still　unclear.　The　aim　of　this　study　was　to　clarify　the　hemodynamic　effects　BJUT-II　VAD　under　pulsatile　support　mode　on　the　aorta.　Material/Methods:　Computational　fluid　dynamics　(CFD)　studies,　based　on　a　patient-specific　aortic　geometric　model,　were　conducted.　Wall　shear　stress　(WSS),　averaged　WSS　(avWSS),　oscillatory　shear　index　(OSI),　and　averaged　helicity　density　(Ha)　were　calculated　to　compare　the　differences　in　hemodynamic　effects　between　pulsatile　support　mode　and　constant　speed　mode.　Results:　The　results　show　that　avWSS　under　pulsatile　support　mode　is　significantly　higher　than　that　under　constant　speed　mode　(0.955Pa　vs.　0.675Pa).　Similarly,　the　OSI　value　under　pulsatile　mode　is　higher　than　that　under　constant　speed　mode　(0.104　vs.　0.057).　In　addition,　Ha　under　pulsatile　mode　for　all　selected　cross-sections　is　larger　than　that　under　constant　mode.　Conclusions:　BJUT-II　VAD,　under　pulsatile　control　mode,　may　prevent　atherosclerosis　lesions　and　aortic　remodeling.　The　precise　effects　of　pulsatile　support　mode　on　atherosclerosis　and　aortic　remodeling　need　to　be　further　studied　in　animal　experiments.