The　use　of　metal-organic　frameworks　(MOFs)　as　heterogeneous　catalyst　for　oxidation　reactions　developed　in　recent　years　is　reviewed.　Because　of　their　unique　structural　features　and　outstanding　physical/chemical　properties,　including　metal　or　organic　active　sites　in　pore　surface,　high　porosity,　large　surface　areas,　and　tailorable　pore　properties,　MOFs　are　promising　and　favorable　for　application　in　various　catalytic　reactions.　In　this　review,　the　applications　of　MOFs　in　catalytic　oxidation　as　catalysts　or　as　supports　of　catalytic　active　species　are　discussed.　Catalytic　MOFs　with　coordinatively　unsaturated　metal　active　sites　and　MOFs　supported　metal　nanoparticles　(MNPs),　polyoxometalates　(POMs),　and　metalloporphyrins　are　emphasized.　Catalytic　oxidization　of　varieties　of　organic　molecules,　including　alkanes,　benzylic　hydrocarbons,　olefins,　alcohols,　phenols,　and　sulfur　compounds,　as　well　as　small　inorganic　molecules,　including　CO　and　water　in　MOFs　and/or　MOFs　supported　catalysts　are　summarized.　In　addition,　the　application　of　MOFs　in　the　oxidation　of　organic　dyes　and　biomimetic　catalysis　is　also　discussed.　Catalytic　performances　of　these　MOFs　and　MOFs　supported　catalysts　are　evaluated　from　the　stability,　heterogeneity,　and　shape/size　selectivity,　as　well　as　precipitation　of　the　active　species　aspects.　Finally,　the　development　trend　of　MOFs　in　the　catalytic　applications　is　prospected.