We　have　created　ZnS　nanoparticles　using　pulsed　laser　ablation　of　ceramic　target　in　water　with　an　aim　to　produce　nanoparticles　with　uniform　distribution　of　the　size.　The　particle　size,　structure,　and　physical　properties　were　systematically　investigated　by　X-ray　diffraction　(XRD),　Raman　spectra,　high-resolution　transmission　electron　microscopy　(HRTEM),　selected　area　electron　diffraction　(SAED),　and　energy-dispersive　spectroscopy.　The　ZnS　nanoparticles　were　confirmed　from　XRD,　Raman　and　SAED　patterns　to　possess　the　sphalerite　structure.　Chemical　composition　of　the　ZnS　nanoparticles　was　found　to　be　stoichiometric.　HRTEM　images　exhibited　well-arranged　lattices　with　the　space　of　0.274　nm　for　(200)　plane　and　that　of　0.317　nm　for　(111)　plane.　The　present　results　demonstrate　that　pulsed　laser　ablation　in　water　is　effective　and　promising　to　create　nanoparticles　with　controllable　size　in　a　large　scale.