收录:
摘要:
In the presence of 10 mol% of Na2CO3, the desired imidazolidine-spirooxindoles were obtained in 81-99% yield with up to 99 : 1 dr by means of the diastereoselective [3 + 2] cycloaddition of N-acylhydrazine-derived imines with 3-isothiocyanato oxindoles. Single-crystal X-ray structure analysis was conducted to determine the relative stereochemistry of the imidazolidine-spirooxindoles. Diastereoselective access to the imidazolidine-spirooxindoles was hypothesized by the proposed mechanism.
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来源 :
RSC ADVANCES
ISSN: 2046-2069
年份: 2016
期: 33
卷: 6
页码: 27690-27695
3 . 9 0 0
JCR@2022
ESI学科: CHEMISTRY;
ESI高被引阀值:221
中科院分区:3
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