Silver　nanoparticle　surface　morphologies　can　be　controlled　using　ultraviolet　light　or　visible　light-emitting　diode　(LED)-assisted　photonic　reduction　of　Ag　ions　in　solution.　Ultraviolet　nanosecond　laser　interference　lithography　(LIL)　is　a　cost-effective　method　for　fabricating　periodic　structures　in　a　polymer　matrix,　and　in　this　work,　we　combine　with　photonic　reduction　to　produce　novel　nanostructured　substrates.　Differing　reduction　times　result　in　differing　fringe　widths　and　nanoparticle　sizes,　with　nanoparticle　shape　gradually　changing　from　spherical　to　plate-shaped　with　increasing　(365　to　615　nm)　excitation　wavelengths.　Such　nanostructured　substrates,　when　utilized　for　surface-enhanced　Raman　spectroscopy　(SERS),　realized　analytical　enhancement　factors　for　naproxen　of　about　10(5)　with　plate-shaped　nanoparticles,　which　was　at　least　ten　times　greater　than　the　enhancement　afforded　by　spherical　nanoparticles.　A　three-dimensional　finite　element　method　simulating　localized　surface　plasmon　resonance　properties　of　these　controlled　silver　structures　demonstrated　nanostructured　plates　effectively　enhanced　local　electrical　fields.　Our　results　demonstrate　that　multi-wavelength　photonic　reduction　integrated　with　LIL　is　an　excellent　means　of　providing　sensitive　substrates　for　SERS.