In　the　presence　of　cinchona-thiourea　organocatalyst　C1,　the　developed　organocatalytic　three-component　cascade　reaction　of　isatins,　malononitrile,　and　2-hydroxynaphthalene-1,4-diones　readily　proceeded　to　furnish　chiral　pyranonaphthoquinone-fused　spirooxindoles　in　excellent　chemical　yields　and　high　enantioselectivities　(up　to　99%　yield　and　97%ee).　The　absolute　configurations　of　the　spirooxindoles　were　assigned　on　the　basis　of　an　X-ray　single　crystal　structure.　Moreover,　a　reaction　mechanism　is　proposed　that　accounts　for　the　stereocontrolled　formation　of　the　chiral　spirooxindoles,.