This　paper　develops　a　mathematical　formulation　to　model　and　optimise　site　facility　locations　inside　a　construction　site　for　a　construction　project＇s　different　stages.　The　existence　and　dimensions　of　a　construction　project＇s　available　locations　and　site　facilities　can　be　varied　across　the　construction　stages.　Without　proper　planning,　unnecessary　facility　relocations　may　be　required　in　each　construction　stage,　resulting　in　a　higher　construction　cost　and　longer　construction　time　due　to　the　need　to　dismantle　and　set　up　site　facilities.　Site　layout　plans　should　be　optimised　using　a　multiple-stage　model　to　avoid　unnecessary　changes　to　facility　settings　across　construction　stages,　improving　efficiency.　The　proposed　site　layout　problem　with　multiple　construction　stages　is　formulated　as　a　binary-mixed-integer-linear　programme,　which　can　be　solved　by　a　standard　branch-and-bound　algorithm　using　the　commercial　software　package　LINGO.　The　mathematical　objective　function　established　in　the　solution　process　aims　to　minimise　the　total　cost,　which　consists　of　the　material　transportation　cost　between　the　relevant　site　facilities　and　the　dismantling,　setup　and　relocation　costs　for　all　of　the　involved　site　facilities　in　each　construction　stage.　Numerical　examples　using　the　proposed　mathematical　model　to　optimise　different　site　layout　settings　for　a　construction　site　are　given,　including　(1)　a　reference　site　layout　plan　using　the　conventional　static　single-stage　approach,　(2)　a　multiple-stage　construction　site　layout　plan　and　(3)　a　multiple-stage　site　layout　plan　with　additional　safety　design　considerations.　(C)　2015　Elsevier　B.V.　All　rights　reserved.