Aims:　The　aim　of　this　study　is　to　investigate　how　the　myocardial　bridge　oppression　affects　the　hoop　stress　of　mural　coronary　artery.　Methods:　The　＂myocardial　bridge　-　coronary　artery＂　simulative　device　records　the　hoop　stress　which　is　changed　by　adjusting　the　external　pressure　of　the　simulated　coronary　artery　and　the　oppression　degree　of　the　respectively.　Results:　Simulation　experiment　in　vitro　indicates　that　the　abnormal　hoop　stress　mainly　occurs　in　the　proximal　end　of　mural　coronary　artery.　As　the　oppression　degree　of　myocardial　bridge　increases,　the　mean　and　the　oscillatory　value　(maximum-minimum)　of　hoop　stress　in　the　proximal　end　increase　markedly.　Conclusions:　The　＂myocardial　bridge　-　coronary　artery＂　simulation　device　can　provide　an　experiment　method　of　studying　the　hoop　stress　influence　on　mural　coronary　artery　in　vitro.