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作者:

Yang Jian (Yang Jian.) | Chen Shu-Shen (Chen Shu-Shen.) | Huangfu Hao-Ran (Huangfu Hao-Ran.) | Liang Pei-Peng (Liang Pei-Peng.) | Zhong Ning (Zhong Ning.)

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EI Scopus SCIE PKU CSCD

摘要:

Assessment of resting-state functional connectivity (FC) has become an important tool in studying brain disease mechanisms. Conclusions from previous resting-state investigations were based upon the hypothesis which assumed that the FC was constant throughout a period of task-free time. However, emerging evidence suggests that it may change over time. Here we investigate the dynamic FC based on the 64 electrodes EEG (electroencephalogram) of 25 healthy subjects in eyes closed (EC) and eyes open (EO) resting-state. A data-driven approach based on independent component analysis, standardized low-resolution tomography analysis, sliding time window, and graph theory are employed. Dynamic changes of FC over time with EC and EO in the visual network, the default mode network etc. are discovered. And the principal component analysis is used to the concatenated dynamic FC matrixes for finding meaningful FC patterns. Our results have complemental the traditional stationary analyses, and revealed novel insights in choosing the type of resting condition in experimental design and EEG clinical research.

关键词:

source localization electroencephalogram dynamical functional connectivity resting-state

作者机构:

  • [ 1 ] [Yang Jian]Beijing Univ Technol, Inst Int WIC, Beijing 100124, Peoples R China
  • [ 2 ] [Chen Shu-Shen]Beijing Univ Technol, Inst Int WIC, Beijing 100124, Peoples R China
  • [ 3 ] [Huangfu Hao-Ran]Beijing Univ Technol, Inst Int WIC, Beijing 100124, Peoples R China
  • [ 4 ] [Zhong Ning]Beijing Univ Technol, Inst Int WIC, Beijing 100124, Peoples R China
  • [ 5 ] [Yang Jian]Beijing Key Lab Magnet Resonance Imaging & Brain, Beijing 100124, Peoples R China
  • [ 6 ] [Chen Shu-Shen]Beijing Key Lab Magnet Resonance Imaging & Brain, Beijing 100124, Peoples R China
  • [ 7 ] [Huangfu Hao-Ran]Beijing Key Lab Magnet Resonance Imaging & Brain, Beijing 100124, Peoples R China
  • [ 8 ] [Liang Pei-Peng]Beijing Key Lab Magnet Resonance Imaging & Brain, Beijing 100124, Peoples R China
  • [ 9 ] [Zhong Ning]Beijing Key Lab Magnet Resonance Imaging & Brain, Beijing 100124, Peoples R China
  • [ 10 ] [Yang Jian]Beijing Int Collaborat Base Brain Informat Wisdom, Beijing 100124, Peoples R China
  • [ 11 ] [Chen Shu-Shen]Beijing Int Collaborat Base Brain Informat Wisdom, Beijing 100124, Peoples R China
  • [ 12 ] [Huangfu Hao-Ran]Beijing Int Collaborat Base Brain Informat Wisdom, Beijing 100124, Peoples R China
  • [ 13 ] [Zhong Ning]Beijing Int Collaborat Base Brain Informat Wisdom, Beijing 100124, Peoples R China
  • [ 14 ] [Liang Pei-Peng]Capital Med Univ, Xuanwu Hosp, Dept Radiol, Beijing 100053, Peoples R China

通讯作者信息:

  • [Yang Jian]Beijing Univ Technol, Inst Int WIC, Beijing 100124, Peoples R China

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来源 :

ACTA PHYSICA SINICA

ISSN: 1000-3290

年份: 2015

期: 5

卷: 64

1 . 0 0 0

JCR@2022

ESI学科: PHYSICS;

ESI高被引阀值:190

JCR分区:4

中科院分区:4

被引次数:

WoS核心集被引频次: 4

SCOPUS被引频次: 8

ESI高被引论文在榜: 0 展开所有

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中文被引频次:

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