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作者:

Zhao, Xi (Zhao, Xi.) | Liu, Youjun (Liu, Youjun.) (学者:刘有军) | Wang, Wenxin (Wang, Wenxin.)

收录:

SCIE

摘要:

Purpose: Sequential graft and Y-type graft are two different surgical procedures in coronary artery bypass grafting (CABG). The hemodynamic environment of them are different, that may cause different short-term surgical result and long-term patency. In this study, the short-term and long-term result of sequential and Y-type graft was discussed by comparing the hemodynamics of them. Materials and Methods: Two postoperative 3-dimensional (3D) models were built by applying different graft on a patient-specific 3D model with serious stenosis. Then zero-dimensional (0D)/3D coupled simulation was carried out by coupling the postoperative 3D models with a 0D lumped parameter model of the cardiovascular system. Results: The flow rate of native coronary arteries and grafts are all calculated and illustrated in this paper. No significant difference of the native coronary arteries flow and graft flow exists between two surgical procedures. The wall shear stress (WSS) and streamline were also depicted. The graft WSS of sequential graft is 19.1% higher than Y-type graft. While flow separation appears at the bifurcation of Y-type graft. Conclusion: The short-term outcomes of sequential graft and Y-type graft are almost the same. But it can be found from the hemodynamics factors that the long-term patency of the sequential graft is better.

关键词:

0D/3D coupling Simulation Computational Fluid Dynamics (Cfill) Coronary Artery Bypass Grafting (CABG) Hemodynamics

作者机构:

  • [ 1 ] [Zhao, Xi]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
  • [ 2 ] [Liu, Youjun]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
  • [ 3 ] [Wang, Wenxin]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China

通讯作者信息:

  • [Zhao, Xi]Beijing Univ Technol, Coll Life Sci & Bioengn, 100 Pingleyuan, Beijing 100124, Peoples R China

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来源 :

MOLECULAR & CELLULAR BIOMECHANICS

ISSN: 1556-5297

年份: 2015

期: 1

卷: 12

页码: 49-66

ESI学科: MOLECULAR BIOLOGY & GENETICS;

ESI高被引阀值:269

JCR分区:4

中科院分区:4

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WoS核心集被引频次: 4

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ESI高被引论文在榜: 0 展开所有

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