Three-dimensionally　ordered　macro/mesoporous　Ce0.6Zr0.3Y0.1O2　(3DOM　CZY)　supported　high-dispersion　Pt　nanoparticles　(x　wt　%　Pt/3DOM　CZY,　x　=　0.6,　1.1,　and　1.7)　were　successfully　synthesized　via　the　cetyltrimethylammonium　bromide/triblock　copolymer　P123　assisted　gas　bubbling　reduction　route.　The　3DOM　CZY　and　x　wt　%　Pt/3DOM　CZY　samples　exhibited　a　high　surface　area　of　84-94　m(2)/g.　Pt　nanoparticles　(NPs)　with　a　size　of　2.6-4.2　nm　were　uniformly　dispersed　on　the　surface　of　3DOM　CZY.　The　1.1　wt　%　Pt/3DOM　CZY　sample　showed　excellent　catalytic　performance,　giving　a　T-90%　value　at　598　degrees　C　at　gas　hourly　space　velocity　(GHSV)　of　30000　mL/(g　h)　and　the　highest　turnover　frequency　(TOFPt)　of　6.98　X　10(-3)　mol/(mol(Pt)　s)　at　400　degrees　C　for　methane　combustion.　The　apparent　activation　energy　(64　kJ/mol)　over　1.1　wt　%　Pt/3DOM　CZY　was　much　lower　than　that　(95　kJ/mol)　over　Bulk　CZY.　The　effects　of　water　vapor　and　SO2　on　the　catalytic　activity　of　1.1　wt　%　Pt/3DOM　CZY　were　also　examined.　It　is　concluded　that　the　excellent　catalytic　activity　of　1.1　wt　%　Pt/3DOM　CZY　was　associated　with　its　high　oxygen　adspecies　concentration,　good　low-temperature　reducibility,　and　strong　interaction　between　Pt　NPs　and　CZY　as　well　as　large　surface　area　and　unique　nanovoid-walled　3DOM　structure.