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作者:

Zhang, X. C. (Zhang, X. C..) | Liu, S. Q. (Liu, S. Q..) | Ren, H. X. (Ren, H. X..) | Wen, Y. (Wen, Y..) | Zeng, Y. J. (Zeng, Y. J..)

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Scopus SCIE

摘要:

Simple spikes and complex spikes are two distinguishing features in neurons of the cerebellar cortex; the motor learning and memory processes are dependent on these firing patterns. In our research, the detailed firing behaviors of Purkinje cells were investigated using a computer compartmental neuronal model. By means of application of numerical stimuli, the abundant dynamical properties involved in the multifarious firing patterns (such as the Max-Min potentials of each spike and period-adding/perioddoubling bifurcations) appeared. Neuronal interspike interval (ISI) diagrams, frequency diagrams, and current-voltage diagrams for different ions were plotted. Finally, Poincar, mapping was used as a theoretical method to markedly distinguish timing of the above firing patterns. Our simulation results indicated that firing of Purkinje cells varies dynamically depending on different electrophysiological parameters of these neurons, and the respective properties may play significant roles in the formation of the mentioned characteristics of dynamical firings in the coding strategy for information processing and learning.

关键词:

computer compartmental model current-voltage diagram frequency interspike intervals (ISIs) Max-Min potential Poincare mapping Purkinje cell

作者机构:

  • [ 1 ] [Zhang, X. C.]S China Univ Technol, Dept Math, Guangzhou 510641, Guangdong, Peoples R China
  • [ 2 ] [Liu, S. Q.]S China Univ Technol, Dept Math, Guangzhou 510641, Guangdong, Peoples R China
  • [ 3 ] [Ren, H. X.]S China Univ Technol, Dept Math, Guangzhou 510641, Guangdong, Peoples R China
  • [ 4 ] [Wen, Y.]S China Univ Technol, Dept Math, Guangzhou 510641, Guangdong, Peoples R China
  • [ 5 ] [Zeng, Y. J.]Beijing Univ Technol, Ctr Biomed Engn, Beijing, Peoples R China

通讯作者信息:

  • [Liu, S. Q.]S China Univ Technol, Dept Math, Guangzhou 510641, Guangdong, Peoples R China

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来源 :

NEUROPHYSIOLOGY

ISSN: 0090-2977

年份: 2015

期: 1

卷: 47

页码: 2-10

0 . 5 0 0

JCR@2022

ESI学科: NEUROSCIENCE & BEHAVIOR;

ESI高被引阀值:166

JCR分区:4

中科院分区:4

被引次数:

WoS核心集被引频次: 1

SCOPUS被引频次: 1

ESI高被引论文在榜: 0 展开所有

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