The　discovery　of　denitrifying　anaerobic　methane　oxidation　with　nitrite　as　electron　acceptor　mediated　by　CandidatusMethylomirabilis　oxyfera＇　connected　the　biogeochemical　carbon　and　nitrogen　cycle　in　a　new　way.　However,　it　is　important　to　have　a　comprehensive　understanding　about　the　distribution　of　M.oxyfera-like　bacteria　in　the　terrestrial　realm,　especially　the　wetland　ecosystems　that　are　known　as　the　largest　natural　source　of　atmospheric　methane.　Here,　our　molecular　evidence　demonstrated　that　a　wide　geographical　distribution　of　M.oxyfera-like　bacteria　at　oxic/anoxic　interfaces　of　various　wetlands　(n=91)　over　the　Chinese　territory.　Intriguingly,　the　M.oxyfera-like　bacteria　were　detected　in　some　extreme　environments,　indicating　that　M.oxyfera-like　bacteria　occupied　a　wide　range　of　habitats.　Quantitative　polymerase　chain　reaction　estimated　that　the　abundance　of　M.oxyfera-like　bacteria　ranged　from　2.2x10(3)　to　2.3x10(7)　copiesg(-1)　dry　soil,　and　up　to　around　0.62%　of　the　total　number　of　bacteria.　Moreover,　the　M.oxyfera-like　bacteria　showed　high　biodiversity　in　wetland　ecosystems　based　on　the　analysis　of　462　pmoA　and　287　16S　rRNA　gene　sequences.　The　current　study　revealed　the　widespread　distribution　and　biogeography　of　M.oxyfera-like　bacteria　in　the　terrestrial　system.