Precise　fabrication　of　subtle　nanogaps　amid　individual　nanoparticles　or　between　adjacent　ones　to　obtain　the　highest　SERS　enhancement　is　still　a　challenge.　Here,　we　reported　a　novel　approach　for　fabricating　core-shell-satellite　3D　magnetic　microspheres　(CSSM),　that　easily　form　a　porous　1.5　nm　PEI　interlayer　to　accommodate　molecules　and　create　sufficient　hotspots　between　the　inner　Fe3O4@Ag　core　and　outer　assembled　Au@Ag　satellites.　Experiments　and　finite-difference　time-domain　(FDTD)　simulation　demonstrated　that　the　enhancement　factor　(EF)　was　about　2.03　x　10(8)　and　6.25　x　10(6),　respectively.　In　addition,　the　micro-scale　magnetic　core　endowed　the　CSSM　with　a　superior　magnetic　nature,　which　enabled　easy　separation　and　further　enhanced　Raman　signals　due　to　enrichment　of　targeted　analytes　and　abundant　interparticle　hotspots　created　by　magnetism-induced　aggregation.　Our　results　further　demonstrated　that　the　CSSM　is　expected　to　be　a　versatile　SERS　substrate,　which　has　been　verified　by　the　detection　of　the　adsorbed　pesticide　thiram　and　the　non-adsorbed　pesticide　paraquat　with　a　detection　limit　as　low　as　5　x　10(-12)　M　and　1　x　10(-10)　M,　respectively.　The　novel　CSSM　can　overcome　the　long-standing　limitations　of　SERS　for　the　trace　characterization　of　various　analytes　in　different　solutions　and　promises　to　transform　SERS　into　a　practical　analytical　technique.