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作者:

Guo, Xuemei (Guo, Xuemei.) | Nan, Qun (Nan, Qun.) | Qiao, Aike (Qiao, Aike.) (学者:乔爱科)

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摘要:

Considering the blood coagulation induced by the heating of radio frequency ablation (RFA) and the mechanism of aneurysm embolization, we proposed that RFA may be used to treat arterial aneurysm. But the safety of this method should be investigated. A finite element method (FEM) was used to simulate temperature and pressure distribution in aneurysm with different electrode position, electric field intensity and ablation time. When the electrode is in the middle of the artery aneurysm sac, temperature rose clearly in half side of artery aneurysm, which is not suitable for RFA. Temperature rose in the whole aneurysm when the electrode is under the artery aneurysm orifice, which is suitable for the ablation therapy. And in this way, the highest temperature was 69.585 degrees C when power was 5.0 V/mm with 60 s. It can promote the coagulation and thrombosis generation in the aneurysm sac while the outside tissue temperature rises a little. Meanwhile, the pressure (10 Pa) at the top of aneurysm sac with electrode insertion is less than that (60 Pa) without electrode, so electrode implant may protect the aneurysm from rupture. The results can provide a theoretical basis for interventional treatment of aneurysm with RFA.

关键词:

finite element method (FEM) temperature distribution Radiofrequency ablation (RFA) arterial aneurysm

作者机构:

  • [ 1 ] [Guo, Xuemei]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 2 ] [Nan, Qun]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China
  • [ 3 ] [Qiao, Aike]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China

通讯作者信息:

  • [Nan, Qun]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing, Peoples R China

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来源 :

BIO-MEDICAL MATERIALS AND ENGINEERING

ISSN: 0959-2989

年份: 2015

卷: 26

页码: S271-S277

1 . 0 0 0

JCR@2022

ESI学科: CLINICAL MEDICINE;

ESI高被引阀值:216

JCR分区:4

中科院分区:4

被引次数:

WoS核心集被引频次: 1

SCOPUS被引频次: 2

ESI高被引论文在榜: 0 展开所有

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