With　the　increasing　of　labor　salaries,　the　RMB　exchange　rate,　resource　product　prices　and　requirements　of　environmental　protection,　inexpensive　labor　and　land　are　no　longer　the　decisive　factor　of　regional　competitiveness.　From　this　perspective,　China　needs　to　shift　from　the　extensive　development　mode　to　the　sustainable　development　mode.　Science　and　technology　resources　rational　allocation　is　one　of　the　key　issues　in　sustainable　development.　Based　on　the　counties　(districts)　data　of　Zhejiang　Province　in　China,　this　paper　portrays　the　spatial　variation　of　regional　sustainable　development　level　of　this　area.　This　paper　finds　that　counties　tend　to　cluster　in　groups　with　the　same　sustainable　development　level,　and　this　agglomeration　trend　has　been　enforced　during　the　past　several　years.　It　then　testifies　to　the　relationship　between　the　allocation　of　science　and　technology　resources　and　local　sustainable　development,　identifies　science　and　technology　human　resources,　financial　resources　and　environmental　resource　are　positively　related　to　local　sustainable　development,　except　government　financial　support.　The　economic　level　has　a　negative　relationship　with　regional　sustainable　development.　This　is　because　the　development　of　the　Zhejiang　economy　grown　at　the　expense　of　the　environment　and　ecosystem.　Some　advice　is　given　according　to　the　empirical　analysis　result.