We　sought　to　investigate　the　effects　of　endovascular　stents　with　different　links　for　treating　stenotic　vertebral　artery　and　to　determine　the　relationship　between　the　shape　of　the　link　and　in-stent　restenosis　(ISR).　We　also　attempted　to　provide　scientific　guidelines　for　stent　design　and　selection　for　clinical　procedures.　Models　of　three　types　of　stent　with　different　links　(L-stent,　V-stent,　and　S-stent)　and　an　idealized　stenotic　vertebral　artery　were　established.　The　deployment　procedure　for　the　stent　in　the　stenotic　vertebral　artery　was　simulated　for　solid　mechanics　analysis.　Next,　the　deformed　models　were　extracted　to　construct　the　blood　flow　domain,　and　numerical　simulations　of　the　hemodynamics　in　these　models　were　performed　using　the　finite　element　method.　The　numerical　results　demonstrated　that:　(1)　Compared　with　the　L-stent　and　V-stent,　the　S-stent　has　a　better　flexibility　and　induces　less　stress　in　the　stent　strut.　Furthermore,　less　stress　is　generated　in　the　arterial　wall.　(2)　Vascular　straightening　is　scarcely　influenced　by　the　shape　of　the　link,　but　it　is　closely　related　to　the　flexibility　of　the　stent.　(3)　The　S-stent　has　the　smallest　foreshortening　among　the　three　types　of　stents.　(4)　Compared　with　the　V-stent　and　S-stent,　the　L-stent　causes　a　smaller　area　with　low　wall　shear　stress,　less　blood　stagnation　area,　and　better　blood　flow　close　to　the　artery　wall.　From　the　viewpoint　of　the　combination　of　solid　mechanics　and　hemodynamics,　the　S-stent　has　better　therapeutic　effects　because　of　its　lower　potential　for　inducing　ISR　and　its　better　prospects　in　clinical　applications　compared　with　the　L-stent　and　V-stent.