The　nanocatalysts　of　Pd　nanocubes　supported　on　SiO2,　TiO2　and　MgO　were　prepared　and　the　CO　oxidation　activities　over　the　three　catalysts　were　evaluated.　The　acid-basic　properties　of　the　support　materials　were　determined　using　the　temperature-programmed　desorptions　of　NH3　(NH3-TPD)　and　CO2　(CO2-TPD).　The　CO　adsorptions　over　the　three　catalysts　were　investigated　by　the　diffuse　reflectance　infrared　Fourier　transform　(DRIFT).　It　was　found　that　the　Pd/MgO　catalyst　showed　the　strongest　ability　to　adsorb　CO　molecules　and　performed　best　for　CO　oxidation.　(C)　2013　Elsevier　B.V.　All　rights　reserved.