Alcohol-permselective　membranes　may　play　an　increasingly　important　role　in　bioalcohol　production.　Developments　for　this　membrane　mostly　involve　hybrid　membranes.　Obtaining　high　compatibility　and　nanodispersion　of　inorganic　nanoparticles　in　the　polymer　matrix　is　the　key　to　fabricating　hybrid　membranes　with　high　pervaporation　performance.　In　this　study,　a　homogeneous,　nanodisperse　ZIF-8/PDMS　membrane　was　prepared　by　repeated　immersion　of　a　polysulfone　supporting　membrane　in　a　dilute　ZIF-8/PDMS　suspension　and　subsequent　removal　of　defects　using　a　concentrated　PDMS　solution.　To　improve　the　nanoscale　dispersion　of　ZIF-8,　the　nascent　ZIF-8　suspension　was　directly　dispersed　in　a　PDMS　solution　without　drying.　This　procedure　avoids　aggregation　and　redispersion　of　ZIF-8　nanoparticles　after　forming　a　powder.　Analyses　confirmed　that　the　ZIF-8/PDMS　dispersion　effectively　diminished　aggregation　between　nanoparticles　and　led　to　the　formation　of　a　well-dispersed　ZIF-8/PDMS　membrane.　A　homogeneous　and　thin　ZIF-8/PDMS　permselective　layer　was　obtained　by　adjusting　the　preparation　conditions.　The　prepared　ZIF-8/PDMS　membrane　exhibited　a　high　separation　factor　(52.81)　and　high　flux　(2800.5　g　m(-2)　h(-1))　in　the　separation　of　5.0　wt%　n-butanol-water　solution　at　80　degrees　C.　By　comparing　the　powder-dispersed　ZIF-8/PDMS　hybrid　membrane　with　the　suspension-dispersed　ZIF-8/PDMS　membrane,　we　found　that　the　latter　showed　much　higher　performance　in　butanol　separation.　Therefore,　the　nanodisperse　ZIF-8/PDMS　membrane　has　great　potential　applications　for　in　situ　recovery　of　biobutanol.