A　new　antiferromagnetic　metal-organic　framework,　{[(CH3)(2)NH2](2)[Mn-8(mu(4)-O)(3)(thb)(6)(solvent)(6)]}(n)　(thb　=　2,5-thiophenedicarboxylate)　with　octanuclear　Mn-8(mu(4)-O)(3)(COO)(12)　clusters　as　secondary　building　unit　was　synthesized　and　characterized,　which　has　a　pcu　network　topology　when　considering　the　Mn-8　cluster　as　a　6-connected　node　and　each　two　double-linking　thb　ligands　as　a　linker.　A　new　antiferromagnetic　3-D　metal-organic　framework　{[(CH3)(2)NH2](2)[Mn-8(mu(4)-O)(3)(thb)(6)(solvent)(6)]}(n)　(1,　thb　=　2,5-thiophenedicarboxylate)　with　octanuclear　Mn-8(mu(4)-O)(3)(COO)(12)　secondary　building　unit　(SBU)　has　been　solvothermally　synthesized　and　characterized　by　single-crystal　X-ray　diffraction,　thermogravimetric　analysis,　and　infrared　spectroscopy.　Considering　this　Mn-8　SBU　as　a　6-connected　node,　the　overall　framework　of　1　has　a　pcu　topology.　It　is　interesting　that　the　high　symmetry　Mn　cluster　shows　a　double-linked　connection　between　two　SBUs　and　exhibits　an　antiferromagnetic　property.