This　study　investigates　the　dynamic　response　of　structures　and　the　effect　of　soil-structure　interaction　for　flexible　structures　supported　by　pile　foundations　located　in　non-liquefiable　and　liquefiable　sites　as　well　as　a　rigid　foundation.　A　series　of　large-scale　shaking　table　experiments　were　performed,　and　accelerations　and　dynamic　displacements　of　model　superstructures　were　recorded　during　the　shaking　events.　It　was　observed　that　the　structure　in　non-liquefiable　soil　deposits　had　the　highest　accelerations　due　to　the　amplification　of　ground　motion　within　the　soil.　On　the　other　hand,　the　accelerations　of　the　structure　in　liquefied　site　was　small　due　to　the　increased　dissipation　of　seismic　energy.　The　structures　founded　on　soil　experienced　residual　(permanent)　lateral　displacements,　with　the　permanent　lateral　displacement　and　tilting　of　the　structure　in　the　liquefied　site　being　much　larger.　The　structure　on　rigid　foundation　(i.e.　foundation　on　rock　or　fixed　base)　experienced　high　accelerations　and　oscillatory　displacement　as　the　seismic　energy　could　not　be　dissipated.　Therefore,　structures　in　liquefiable　soil　are　prone　to　overturning　damage　due　to　failure　of　their　foundations.　Furthermore,　the　base　shear　force　of　the　structure　in　the　non-liquefied　site　was　significantly　larger　than　that　in　the　liquefied　site　and　fixed-base,　indicating　it　would　be　more　susceptible　to　shear　failure.　On　the　other　hand,　the　fixed-base　structure　experienced　relatively　large　acceleration　and　dynamic　displacement　responses,　which　indicates　increased　seismic　demands　on　its　structural　members.