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Author:

Su, Yansen (Su, Yansen.) | Wang, Shudong (Wang, Shudong.) | Li, Eryan (Li, Eryan.) | Song, Tao (Song, Tao.) | Yu, Hui (Yu, Hui.) | Meng, Dazhi (Meng, Dazhi.)

Indexed by:

Scopus SCIE

Abstract:

External stimuli may activate the stress response in Arabidopsis thaliana. The molecules which play important roles in the stress response have been widely studied. However, the interactions, especially logic interactions, among these molecules, need to be studied. In this paper, logic networks are constructed based on gene expression profiles of Arabidopsis under the normal condition and four different stimuli conditions, respectively. It is found that the distribution of different types of 2-order logics in the gene logic network under the normal condition is different from the others. Furthermore, the logic networks of genes which play important roles are constructed and their dynamics are simulated. It is then observed that the number of attractors in the logic network for Arabidopsis under the normal condition is less than those under four external stimuli. It is also observed that the number of attractors with large attraction domain in the logic network for Arabidopsis under the normal condition is greater than those under four external stimuli. The results show that the distribution of different types of 2-order logics and the number of attractors clearly distinguish logic network under the normal condition from those under external stimuli conditions. Our studies will provide the theoretical basis for experimental studies on the stress response of Arabidopsis.

Keyword:

network dynamics network structure high-order logic gene network Arabidopsis systems biology

Author Community:

  • [ 1 ] [Su, Yansen]Huazhong Univ Sci & Technol, Dept Control Sci & Engn, Wuhan 430074, Hunan, Peoples R China
  • [ 2 ] [Song, Tao]Huazhong Univ Sci & Technol, Dept Control Sci & Engn, Wuhan 430074, Hunan, Peoples R China
  • [ 3 ] [Yu, Hui]Huazhong Univ Sci & Technol, Dept Control Sci & Engn, Wuhan 430074, Hunan, Peoples R China
  • [ 4 ] [Wang, Shudong]Shandong Univ Sci & Technol, Inst Informat Sci & Engn, Qingdao 266510, Shandong, Peoples R China
  • [ 5 ] [Li, Eryan]Shandong Univ Sci & Technol, Inst Informat Sci & Engn, Qingdao 266510, Shandong, Peoples R China
  • [ 6 ] [Meng, Dazhi]Shandong Univ Sci & Technol, Inst Informat Sci & Engn, Qingdao 266510, Shandong, Peoples R China
  • [ 7 ] [Meng, Dazhi]Beijing Univ Technol, Coll Appl Sci, Beijing 100124, Peoples R China

Reprint Author's Address:

  • [Meng, Dazhi]Shandong Univ Sci & Technol, Inst Informat Sci & Engn, Qingdao 266510, Shandong, Peoples R China

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Source :

CURRENT BIOINFORMATICS

ISSN: 1574-8936

Year: 2013

Issue: 2

Volume: 8

Page: 244-252

4 . 0 0 0

JCR@2022

ESI Discipline: COMPUTER SCIENCE;

JCR Journal Grade:2

CAS Journal Grade:4

Cited Count:

WoS CC Cited Count: 2

SCOPUS Cited Count: 2

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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