• 综合
  • 标题
  • 关键词
  • 摘要
  • 学者
  • 期刊-刊名
  • 期刊-ISSN
  • 会议名称
搜索

作者:

Shen, Feng (Shen, Feng.) | Li, Zonghe (Li, Zonghe.) | Xue, Sen (Xue, Sen.) | Li, Mengqi (Li, Mengqi.) | Liu, Zhaomiao (Liu, Zhaomiao.) (学者:刘赵淼)

收录:

EI SCIE

摘要:

Particle/cell separation from a mixture using a hydrodynamic vortex has been attracting much interest for the isolation of circulating tumor cells in basic biological studies and clinical applications. However, some issues regarding the particle recirculating orbits within the vortex in microcavities remain unclear. In this work, using micro-particle image velocimetry and a high-speed microscopy system, we quantitatively investigate the effects of inlet Reynolds numbers (Re) on the microcavity flow characteristics and particle recirculating behavior. The results show that due to the evolution of microcavity flow patterns (Re = 15-313), the particle orbit topology expands gradually, developing from a single small orbit (Re = 39-79) to a single semicircular orbit (98-117), then to alternating double orbits (Re = 136-215), and at last to a single large orbit (Re = 254-352). The alternating double orbits are observed for the first time. The particle orbit periods and topologies (lengths and area) have also been characterized. Moreover, the variations of the recirculating particle velocity are also quantitatively measured. The results deepen the fundamental understanding of particle recirculating behavior and could provide useful guidance for vortex-based microfluidics.

关键词:

cell separation microcavity microfluidics particle particle orbit vortex

作者机构:

  • [ 1 ] [Shen, Feng]Beijing Univ Technol, Fac Mat & Mfg, Beijing 100124, Peoples R China
  • [ 2 ] [Li, Zonghe]Beijing Univ Technol, Fac Mat & Mfg, Beijing 100124, Peoples R China
  • [ 3 ] [Xue, Sen]Beijing Univ Technol, Fac Mat & Mfg, Beijing 100124, Peoples R China
  • [ 4 ] [Li, Mengqi]Beijing Univ Technol, Fac Mat & Mfg, Beijing 100124, Peoples R China
  • [ 5 ] [Liu, Zhaomiao]Beijing Univ Technol, Fac Mat & Mfg, Beijing 100124, Peoples R China
  • [ 6 ] [Shen, Feng]Beijing Univ Technol, Inst Adv Mech Engn, Beijing 100124, Peoples R China
  • [ 7 ] [Li, Zonghe]Beijing Univ Technol, Inst Adv Mech Engn, Beijing 100124, Peoples R China
  • [ 8 ] [Xue, Sen]Beijing Univ Technol, Inst Adv Mech Engn, Beijing 100124, Peoples R China
  • [ 9 ] [Li, Mengqi]Beijing Univ Technol, Inst Adv Mech Engn, Beijing 100124, Peoples R China
  • [ 10 ] [Liu, Zhaomiao]Beijing Univ Technol, Inst Adv Mech Engn, Beijing 100124, Peoples R China
  • [ 11 ] [Shen, Feng]Beijing Univ Technol, Beijing Key Lab Adv Mfg Technol, Beijing 100124, Peoples R China

通讯作者信息:

  • 刘赵淼

    [Liu, Zhaomiao]Beijing Univ Technol, Fac Mat & Mfg, Beijing 100124, Peoples R China;;[Liu, Zhaomiao]Beijing Univ Technol, Inst Adv Mech Engn, Beijing 100124, Peoples R China

电子邮件地址:

查看成果更多字段

相关关键词:

来源 :

JOURNAL OF PHYSICS D-APPLIED PHYSICS

ISSN: 0022-3727

年份: 2021

期: 2

卷: 54

3 . 4 0 0

JCR@2022

ESI学科: PHYSICS;

ESI高被引阀值:7

被引次数:

WoS核心集被引频次: 11

SCOPUS被引频次: 12

ESI高被引论文在榜: 1 展开所有

  • 2021-7

万方被引频次:

中文被引频次:

近30日浏览量: 3

在线人数/总访问数:3851/2928243
地址:北京工业大学图书馆(北京市朝阳区平乐园100号 邮编:100124) 联系我们:010-67392185
版权所有:北京工业大学图书馆 站点建设与维护:北京爱琴海乐之技术有限公司