Objective:　To　investigate　the　effect　of　embryonic　neural　stem　cell　(NSC)　transplantation　on　cerebral　infarction　sequelae.　Methods:　From　June　2004　to　June　2008,　embryonic　NSCs　were　implanted　into　the　ipsilateral　basal　ganglia　region　in　21　patients　with　cerebral　infarction,　using　stereotactic　technology.　The　function　independence　measure　(FIM)　was　used　to　evaluate　motor　function　and　quality　of　life　in　the　21　patients　before　treatment,　and　at　1　and　6　months　after　treatment.　FIM　was　regarded　as　effective　if　elevated　by　＞=　1　point.　Results:　Clinical　symptoms　improved　at　an　effective　rate　of　80.95%　(17/21　cases).　The　FIM　scores　were　93.76　+/-　6.83　at　1　month　after　treatment,　which　was　significantly　higher　than　91.21　+/-　6.42　before　treatment;　however,　they　were　significantly　lower　than　97.45　+/-　7.56　at　6　months　after　treatment.　Patients　undergoing　embryonic　NSC　transplantation　had　no　serious　complications.　Conclusions:　NSC　transplantation　can　improve　cerebral　infarction　sequelae　including　motor　function　and　living　quality　in　patients　to　some　extent.　However,　the　long-term　effect　of　NSC　transplantation　still　needs　further　study.