Protamine sulfate-nanodiamond hybrid nanoparticles as a vector for MiR-203 restoration in esophageal carcinoma cells - 文章详情页

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We　report　an　innovative　approach　for　miRNA-203　delivery　in　esophageal　cancer　cells　using　protamine　sulphate　(PS)-nanodiamond　(ND)　nanoparticles.　The　efficient　delivery　of　miR-203　significantly　suppressed　the　proliferation　and　migration　of　cancer　cells　through　targeting　Ran　and　DNp63,　exhibiting　a　great　potential　for　PS@ND　nanoparticles　in　miRNA-based　cancer　therapy.

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作者机构：

[ 1 ] [Cao, Minjun]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
[ 2 ] [Deng, Xiongwei]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
[ 3 ] [Zhang, Fang]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
[ 4 ] [Xiao, Xiangqian]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
[ 5 ] [Hu, Qin]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
[ 6 ] [Fu, Yongwei]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
[ 7 ] [Sheng, Wang]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
[ 8 ] [Zeng, Yi]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China
[ 9 ] [Su, Shishuai]Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China
[ 10 ] [Wu, Yan]Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China
[ 11 ] [Yang, Burton B.]Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON M4N 3M5, Canada

通讯作者信息：

[Wu, Yan]Natl Ctr Nanosci & Technol, 11 Beiyitiao, Beijing 100190, Peoples R China

电子邮件地址：

wuy@nanoctr.cn |
shengwang@bjut.edu.cn

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