A　sensitive　photodetection　based　on　a　novel　hybrid　CMOS　inverter　has　been　demonstrated.　Unlike　common　photo-current　type　photodetectors,　which　convert　optical　signals　to　current,　the　CMOS　inverter　realizes　voltage-output,　overcoming　the　difficulty　to　monitor　current　signal　in　the　range　ofnA.　The　hybrid　CMOS　logic　inverter　employs　n-channel　MoS(2)nanosheet/perovskite　heterojunction　FET　and　p-channel　organic　pentacene　FET　in　a　planar　architecture.　In　order　to　obtain　high　performance,　we　adopt　the　interdigital　electrodes　for　the　pentacene　FET　to　enhance　the　current　density　of　the　p-channel,　and　stack　perovskite　on　the　MoS(2)channel　to　modify　the　threshold　voltage　of　the　n-channel.　As　a　result,　a　CMOS　inverter　with　a　voltage　gain　of　more　than　ten　is　obtained.　When　V(IN)is　around　the　transition　voltage　(-38　V),　the　inverter　can　obtain　stable　optical　detection　signal,　the　V(OUT)changes　from　6　V　in　dark　to　1　V　under　633　nm　light　exposure.　This　finding　indicates　the　potential　to　fabricate　visible　light　detecting　devices　with　voltage-output　based　on　the　inverter　and　may　be　further　applicable　for　a　photo-logic　circuit.