In　this　paper,　we　developed　a　new　design　and　preparation　method　of　2D　and　3D　composite　metamaterial　with　adjustable　isotropic　negative　hydration　expansion　(NHE)　function　based　on　re-entrant　auxetic　honeycomb.　The　metamaterial　is　composed　of　composite　lattice　microstructure　with　hydrogel　driving　layer　and　re-entrant　framework　and　prepared　by　multi-material　3D　printer.　Experimental,　simulation　and　theoretical　investigation　were　carried　out　to　demonstrate　the　design　method　and　NHE　deformation　effects　of　the　metamaterial.　It　was　shown　that　the　effective　NHE　coefficient　depends　on　the　length　of　the　driving　layer　and　the　straight　bar　connecting　the　lattice　microstructures.　In　addition,　a　non-monotonic　relationship　was　found　between　the　bandings　angle　theta　2　and　the　length　ratio　(s/a)　due　to　the　constraint　effect　on　both　ends　of　the　composite　beam.　Through　the　parameter　design　of　the　lattice　microstructure,　the　NHE　coefficient　of　can　be　adjusted　within　the　range　of　0-22.4%.　For　the　3D　sample,　the　value　of　the　NHE　coefficient　is　among　the　largest　achieved　in　experiments　to　date.　This　work　provides　a　practical　method　for　obtaining　2D　and　3D　metamaterial　with　adjustable　NHE　and　can　be　applied　to　the　design　of　macro-,　microand　nano-metamaterial.　(c)　2020　The　Authors.　Published　by　Elsevier　Ltd.　This　is　an　open　access　article　under　the　CC　BY-NC-ND　license　(http://　creativecommons.org/licenses/by-nc-nd/4.0/).