The　bimodal　mesoporous　silica　modified　with　3-aminopropyltriethoxysilane　was　performed　as　the　aspirin　carrier.　The　samples＇　structure,　drug　loading　and　release　profiles　were　characterized　with　X-ray　diffraction,　scanning　electron　microscopy,　N-2　adsorption　and　desorption,　Fourier　transform　infrared　spectroscopy,　TG　analysis,　elemental　analysis　and　UV-spectrophotometer.　For　further　exploring　the　effects　of　the　bimodal　mesopores　on　the　drug　delivery　behavior,　the　unimodal　mesoporous　material　MCM-41　was　also　modified　as　the　aspirin　carrier.　Meantime,　Korsmeyer-Peppas　equation　f(t)　=　kt(n)　was　employed　to　analyze　the　dissolution　data　in　details.　It　is　indicated　that　the　bimodal　mesopores　are　beneficial　for　unrestricted　drug　molecules　diffusing　and　therefore　lead　to　a　higher　loading　and　faster　releasing　than　that　of　MCM-41.　The　results　show　that　the　aspirin　delivery　properties　are　influenced　considerably　by　the　mesoporous　matrix,　whereas　the　large　pore　of　bimodal　mesoporous　silica　is　the　key　point　for　the　improved　controlled-release　properties.　(C)　2011　Elsevier　Inc.　All　rights　reserved.