• 综合
  • 标题
  • 关键词
  • 摘要
  • 学者
  • 期刊-刊名
  • 期刊-ISSN
  • 会议名称
搜索

作者:

Zhang Yi-sen (Zhang Yi-sen.) | Yang Xin-jian (Yang Xin-jian.) | Wang Sheng-zhang (Wang Sheng-zhang.) | Qiao Ai-ke (Qiao Ai-ke.) (学者:乔爱科) | Chen Jia-liang (Chen Jia-liang.) | Zhang Kun-ya (Zhang Kun-ya.) | Liu Zhi-cheng (Liu Zhi-cheng.) | Zhao Yu-jing (Zhao Yu-jing.) | Zhang Ying (Zhang Ying.) | Luo Bin (Luo Bin.) | Li Chuan-hui (Li Chuan-hui.)

收录:

Scopus SCIE

摘要:

Background Stent placement has been widely used to assist coiling in cerebral aneurysm treatments. The present study aimed to investigate the hemodynamic effects of stenting on wide-necked intracranial aneurysms. Methods Three idealized plexiglass aneurismal models with different geometries before and after stenting were created, and their three-dimensional computational models were constructed. Flow dynamics in stented and unstented aneurismal models were studied using in vitro flow visualization and computational fluid dynamics (CFD) simulations. In addition, effects of stenting on flow dynamics in a patient-specific aneurysm model were also analyzed by CFD. Results The results of flow visualization were consistent with those obtained with CFD simulations. Stent deployment reduced vortex inside the aneurysm and its impact on the aneurysm sac, and decreased wall shear stress on the sac. Different aneurysm geometries dictated fundamentally different hemodynamic patterns and outcomes of stenting. Conclusions Stenting across the neck of aneurysms improves local blood flow profiles. This may facilitate thrombus formation in aneurysms and decrease the chance of recanalization. Chin Med J 2010;123(15):1999-2003

关键词:

computational fluid dynamics hemodynamics intracranial aneurysm stents

作者机构:

  • [ 1 ] [Zhang Yi-sen]Capital Med Univ, Beijing Neurosurg Inst, Dept Intervent Neuroradiol, Beijing 100050, Peoples R China
  • [ 2 ] [Yang Xin-jian]Capital Med Univ, Beijing Neurosurg Inst, Dept Intervent Neuroradiol, Beijing 100050, Peoples R China
  • [ 3 ] [Zhao Yu-jing]Capital Med Univ, Beijing Neurosurg Inst, Dept Intervent Neuroradiol, Beijing 100050, Peoples R China
  • [ 4 ] [Zhang Ying]Capital Med Univ, Beijing Neurosurg Inst, Dept Intervent Neuroradiol, Beijing 100050, Peoples R China
  • [ 5 ] [Luo Bin]Capital Med Univ, Beijing Neurosurg Inst, Dept Intervent Neuroradiol, Beijing 100050, Peoples R China
  • [ 6 ] [Li Chuan-hui]Capital Med Univ, Beijing Neurosurg Inst, Dept Intervent Neuroradiol, Beijing 100050, Peoples R China
  • [ 7 ] [Wang Sheng-zhang]Fudan Univ, Dept Mech & Engn Sci, Shanghai 200433, Peoples R China
  • [ 8 ] [Chen Jia-liang]Fudan Univ, Dept Mech & Engn Sci, Shanghai 200433, Peoples R China
  • [ 9 ] [Qiao Ai-ke]Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100024, Peoples R China
  • [ 10 ] [Zhang Kun-ya]Capital Med Univ, Dept Biomed Engn, Beijing 100050, Peoples R China
  • [ 11 ] [Liu Zhi-cheng]Capital Med Univ, Dept Biomed Engn, Beijing 100050, Peoples R China

通讯作者信息:

  • [Yang Xin-jian]Capital Med Univ, Beijing Neurosurg Inst, Dept Intervent Neuroradiol, Beijing 100050, Peoples R China

查看成果更多字段

相关关键词:

相关文章:

来源 :

CHINESE MEDICAL JOURNAL

ISSN: 0366-6999

年份: 2010

期: 15

卷: 123

页码: 1999-2003

6 . 1 0 0

JCR@2022

ESI学科: CLINICAL MEDICINE;

JCR分区:3

中科院分区:4

被引次数:

WoS核心集被引频次: 20

SCOPUS被引频次: 25

ESI高被引论文在榜: 0 展开所有

万方被引频次:

中文被引频次:

近30日浏览量: 2

在线人数/总访问数:1817/2904790
地址:北京工业大学图书馆(北京市朝阳区平乐园100号 邮编:100124) 联系我们:010-67392185
版权所有:北京工业大学图书馆 站点建设与维护:北京爱琴海乐之技术有限公司