In　recent　years,　the　vehicle　collision　on　bridge　has　brought　huge　economic　losses　and　casualties,　and　these　accidents　have　caused　wide　attention.　The　dynamic　responses　of　reinforced　concrete　bridge　double-column　and　reliability　analysis　under　vehicle　collision　were　carried　out　in　the　present　work.　Firstly,　the　establishment　of　a　detailed　finite　element　cast-in-place　column　model　was　conducted　to　verify　the　rationality　of　reinforced　concrete　model　under　impact　loading.　Then,　the　numerical　model　of　vehicle　collision　on　double-column　bridge　was　established.　The　parameters　of　vehicle　velocity,　section　size,　pier　height　and　concrete　strength　were　investigated　respectively.　The　results　show　that　the　failure　modes　of　punching　shear,　shear　cracks　and　diagonal　shear　are　mainly　dominated　by　the　vehicle　velocity　and　the　section　size　of　pier.　The　multiple　sections　of　pier　show　a　high　stress　state　under　vehicle　collision.　The　peak　shear　forces　at　sections　of　bottom　and　impact　area　increase　gradually　with　the　increase　of　concrete　strength,　and　ifs　remarkable　that　concrete　strength　has　no　noticeable　effect　on　the　shear　force　of　other　sections　under　vehicle　collision.　Lastly,　based　on　the　reliability　theory,　the　shear　failure　probability　of　pier　under　vehicle　collision　was　analyzed　by　Monte　Carlo　method.　The　factors　of　vehicle　velocity,　vehicle　mass,　section　size　of　pier　and　concrete　strength　were　investigated　respectively.　It　provides　a　new　method　for　the　reliability　analysis　of　vehicle　collision　on　bridge.