We　prepare　alpha-Fe2O3　nanosheet　supported　0.38,　0.81,　and　1.36　wt%　Au　(average　particle　size　=　4.0　nm)　nanocatalysts,　and　investigate　their　performance　and　mechanism　for　the　selective　catalytic　oxidation　of　isopropanol　to　acetone.　In　the　presence　of　1.2　vol%　isopropanol　and　40　vol%　O-2,　1.36　wt%　Au/alpha-Fe2O3　exhibits　excellent　catalytic　performance,　due　to　its　moderate　acidic　sites　and　better　redox　properties,　with　acetone　selectivity　and　yield　being　as　high　as　99%　and　95%　at　220　degrees　C,　respectively.　In　addition　to　acetone,　little　propylene,　acetic　acid,　acetaldehyde,　methyl　vinyl　ketone,　2-butanone,　isopropyl　ether,　isopropyl　acetate,　3-penten-2-one,　isopropyl　acrylate,　isopropyl　propionate,　and　2,　4-dimethylfuran　are　detected.　The　possible　reaction　mechanism　is　proposed　for　the　selective　catalytic　oxidation　of　isopropanol　to　acetone　over　the　present　catalysts.　We　believe　the　present　selective　catalytic　oxidation　method,　rather　than　the　traditional　complete　catalytic　oxidation　method,　provides　an　alternative　and　economic　method　for　VOCs　emissions　control.