In　the　past　studies,　electrostatic　layer-by-layer　(LbL)　adsorption　of　oppositely　charged　polyelectrolytes　has　proven　to　be　a　promising　method　for　the　preparation　of　polyelectrolyte　multilayer　membranes　(PEMMs).　Till　now,　this　method　was　mainly　used　to　assemble　flat　sheet　and　tubular　membranes.　Since　hollow　fiber　membrane　has　some　advantages　such　as　high-packing　density,　self-contained　mechanical　support　and　hence　the　consequent　economical　superiority,　this　study　therefore　seeked　to　assemble　inner　skin　hollow　fiber　PEMMs　by　using　a　dynamic　LbL　adsorption　technique.　The　assembly　process　was　successfully　accomplished　by　alternatively　dynamically　filtrating　polyacrylic　acid　(PAA)　and　polyethyleneimine　(PEI)　on　a　hydrolyzed　hollow　fiber　polyacrylonitrile(PAN)　membrane　under　a　negative　pressure　condition.　In　the　case　of　pervaporation　separation　of　95　wt.%　ethanol-water　mixture　(50　C),　the　membrane　obtained　with　only　4.5　and　6.5　bilayers　had　separation　factor　of　245　and　1338　while　the　permeate　fluxes　were　290　and　120　g/(m(2)　h),　respectively.　The　pervaporation　separation　behavior　of　various　alcohol/water　mixtures　with　the　alcohols　being　t-butanol,　2-propanol　and　ethanol　were　also　investigated.　Finally,　scanning　electron　microscopy　and　atomic　force　microscopy　clearly　confirms　a　uniform　and　defect-free　layer　formed　on　the　inner　surface　of　hollow　fiber　support.　Since　different　polyelectrolyte　pairs　could　be　used　to　assemble　PEMMs　for　different　uses,　it　was　expected　that　the　dynamic　negative　pressure　LbL　adsorption　technique　could　also　potentially　be　used　to　prepare　many　types　of　PEMMs　in　other　fields.　(c)　2008　Elsevier　B.V.　All　rights　reserved.