Poly　(vinyl　alcohol)　(PVA)　is　an　excellent　membrane　material　for　preparation　of　hydrophilic　ultrafiltration　(UF)　and　nanofiltration　membranes.　But　its　chemical　constitution　and　water　solubility　infer　the　disadvantage　of　easier　degradation　and　elimination　after　use.　This　study　focuses　on　the　modification　of　interfacial　polymerization　PVA　composite　UF　membrane　with　toluene　diisocyanate　(TDI).　The　effects　of　the　reaction　time　and　PVA,　TDI,　sodium　dodecyl　sulfate　and　sodium　hydroxide　with　different　concentrations　were　investigated　on　the　performances　of　composite　membranes.　Anti-fouling　to　protein　and　oil　was　obtained　when　it　was　compared　with　no　modified　membrane.　Also,　the　recovery　ratio　of　pure　water　flux　of　PVA　modified　UF　membrane　is　higher　than　that　of　support　membrane.